SCHEMBL19082490

SCHEMBL19082490

Oc1cc(O)c(-c2c(F)ccc3ccccc23)cc1-c1cc(Br)ccc1F

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NMUR2 Q9GZQ4 3/20 0.43
HSP90AA1 P07900 2/20 0.41
HSP90AB1 P08238 2/20 0.41
POLB P06746 1/20 0.39
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALOX5 P09917 3/20 0.36
PTGES O14684 1/20 0.36
CYP2A6 P11509 1/20 0.36
RCE1 Q9Y256 1/20 0.35
HPRT1 P00492 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082471 0.86 NMUR2 (0.46) NMUR2HSP90AA1HSP90AB1POLBMAPT
SCHEMBL9108431 0.84 HSP90AA1 (0.49) NMUR2HSP90AA1HSP90AB1POLBMAPT
SCHEMBL19082495 0.82 NMUR2 (0.37) NMUR2HSP90AA1HSP90AB1PTGESCYP2A6
SCHEMBL19082477 0.81 NMUR2 (0.38) NMUR2HSP90AA1HSP90AB1HPGDSMN1; SMN2
SCHEMBL19082466 0.81 NMUR2 (0.38) NMUR2HSP90AA1HSP90AB1MAPTHPGD
SCHEMBL16067918 0.80 NMUR2 (0.50) NMUR2POLBMAPTMEN1HPGD
SCHEMBL19091610 0.79 NMUR2 (0.35) NMUR2ALOX5PTGESCYP2A6HPRT1
SCHEMBL19091030 0.79 MAPT (0.44) NMUR2HSP90AA1HSP90AB1MAPTMEN1
SCHEMBL16067923 0.79 CYP2A6 (0.45) NMUR2POLBMAPTMEN1HPGD
SCHEMBL20321636 0.79 MEN1 (0.51) NMUR2MAPTMEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 NMUR2 2800/4885HSP90AA1 3999/4885HSP90AB1 4434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.