SCHEMBL19082869

SCHEMBL19082869

CCCCc1ccc(-c2ccc(-c3cc(F)c(OCc4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.43
RARA P10276 2/20 0.43
RARG P13631 1/20 0.43
S1PR1 P21453 3/20 0.36
S1PR3 Q99500 2/20 0.36
MPL P40238 6/20 0.35
MAOB P27338 1/20 0.34
FFAR4 Q5NUL3 2/20 0.34
MAPT P10636 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
F10 P00742 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082870 0.96 RARB (0.47) RARBRARARARGS1PR1S1PR3
SCHEMBL19082923 0.95 RARB (0.40) RARBRARARARGS1PR1S1PR3
SCHEMBL19082825 0.94 RARB (0.40) RARBRARARARGS1PR1S1PR3
SCHEMBL16038268 0.93 RARB (0.37) RARBRARARARGS1PR1S1PR3
SCHEMBL19082924 0.92 RARB (0.45) RARBRARARARGS1PR1S1PR3
SCHEMBL19082933 0.92 RARB (0.41) RARBRARARARGS1PR1S1PR3
SCHEMBL19082887 0.91 RARB (0.40) RARBRARARARGS1PR1S1PR3
SCHEMBL19082867 0.91 RARB (0.44) RARBRARARARGMAOBFFAR4
SCHEMBL19082856 0.91 RARB (0.44) RARBRARARARGMAOBFFAR4
SCHEMBL19082929 0.91 RARB (0.43) RARBRARARARGS1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed