SCHEMBL19082924

SCHEMBL19082924

CCCCCc1cc(F)c(OCc2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)cc2)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 11/20 0.45
RARA P10276 3/20 0.44
RARG P13631 1/20 0.44
FFAR4 Q5NUL3 2/20 0.35
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 2/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
NPC1 O15118 1/20 0.33
STAT3 P40763 1/20 0.33
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP3A4 P08684 1/20 0.33
PTGS2 P35354 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082923 0.96 RARB (0.40) RARBRARARARGFFAR4S1PR1
SCHEMBL19082870 0.95 RARB (0.47) RARBRARARARGTSHRHSD17B10
SCHEMBL19082932 0.94 RARB (0.46) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082886 0.94 RARB (0.44) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082928 0.93 RARB (0.47) RARBRARARARGFFAR4TSHR
SCHEMBL19082869 0.92 RARB (0.43) RARBRARARARGFFAR4MAPT
SCHEMBL19082829 0.92 RARB (0.44) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082921 0.92 FFAR4 (0.37) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082889 0.92 RARB (0.46) RARBRARARARGFFAR4TSHR
SCHEMBL19082933 0.91 RARB (0.41) RARBRARARARGFFAR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed