SCHEMBL19082856

SCHEMBL19082856

CCCCc1ccc(-c2cc(F)c(OCc3cc(F)c(F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.44
RARA P10276 2/20 0.44
RARG P13631 1/20 0.44
MAOB P27338 1/20 0.38
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
MAPT P10636 1/20 0.36
FFAR4 Q5NUL3 2/20 0.36
NPC1 O15118 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
F10 P00742 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082867 1.00 RARB (0.44) RARBRARARARGMAOBAKR1C2
SCHEMBL19082821 0.96 RARB (0.49) RARBRARARARGMAOBGPR84
SCHEMBL19082868 0.96 RARB (0.49) RARBRARARARGMAOBGPR84
SCHEMBL19082884 0.95 RARB (0.41) RARBRARARARGMAOBAKR1C2
SCHEMBL16037972 0.92 MAOB (0.40) RARBRARARARGMAOBGPR84
SCHEMBL19082871 0.92 MAOB (0.40) RARBRARARARGMAOBGPR84
SCHEMBL19082869 0.91 RARB (0.43) RARBRARARARGMAOBGPR84
SCHEMBL19082889 0.91 RARB (0.46) RARBRARARARGMAPTFFAR4
SCHEMBL19082929 0.89 RARB (0.43) RARBRARARARGFFAR4NPC1
SCHEMBL19082870 0.88 RARB (0.47) RARBRARARARGGPR84MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed