SCHEMBL19082885

SCHEMBL19082885

CCc1cc(F)c(OCc2ccc(-c3cc(F)c(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.39
MAOB P27338 4/20 0.38
F10 P00742 1/20 0.38
KDM1A O60341 3/20 0.36
RXRA P19793 2/20 0.34
RXRB P28702 2/20 0.34
MAPT P10636 1/20 0.34
FFAR1 O14842 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
MAOA P21397 2/20 0.32
CYP17A1 P05093 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082861 0.94 MAOB (0.41) FFAR4MAOBF10KDM1ARXRA
SCHEMBL19082839 0.94 MAOB (0.41) FFAR4MAOBF10KDM1ARXRA
SCHEMBL19082922 0.90 FFAR4 (0.36) FFAR4MAOBF10KDM1AFFAR1
SCHEMBL19082927 0.90 FFAR4 (0.36) FFAR4MAOBF10KDM1AFFAR1
SCHEMBL19082888 0.88 FFAR4 (0.40) FFAR4MAOBF10FFAR1NPC1
SCHEMBL16038504 0.87 GPR84 (0.39) FFAR4MAOBF10FFAR1NPC1
SCHEMBL19082930 0.86 FFAR4 (0.36) FFAR4MAOBKDM1AFFAR1MAOA
SCHEMBL19082884 0.86 RARB (0.41) FFAR4MAOBF10L3MBTL1NPC1
SCHEMBL16037972 0.85 MAOB (0.40) FFAR4MAOBF10MAPTFFAR1
SCHEMBL19082871 0.85 MAOB (0.40) FFAR4MAOBF10MAPTFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed