SCHEMBL19082871

SCHEMBL19082871

CCCc1ccc(-c2ccc(-c3cc(F)c(OCc4cc(F)c(F)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
FFAR4 Q5NUL3 8/20 0.38
RARB P10826 2/20 0.37
RARA P10276 1/20 0.37
RARG P13631 1/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
F10 P00742 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
MCL1 Q07820 1/20 0.35
FFAR1 O14842 2/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16037972 1.00 MAOB (0.40) MAOBFFAR4RARBRARARARG
SCHEMBL16038504 0.96 GPR84 (0.39) MAOBFFAR4RARBRARARARG
SCHEMBL19082888 0.94 FFAR4 (0.40) MAOBFFAR4RARBRARARARG
SCHEMBL19082856 0.92 RARB (0.44) MAOBFFAR4RARBRARARARG
SCHEMBL19082867 0.92 RARB (0.44) MAOBFFAR4RARBRARARARG
SCHEMBL16038268 0.91 RARB (0.37) MAOBFFAR4RARBRARARARG
SCHEMBL19082821 0.91 RARB (0.49) MAOBRARBRARARARGNPC1
SCHEMBL19082868 0.91 RARB (0.49) MAOBRARBRARARARGNPC1
SCHEMBL16038102 0.89 MAOA (0.42) MAOBFFAR4RARBRARARARG
SCHEMBL19082839 0.88 MAOB (0.41) MAOBFFAR4F10FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed