SCHEMBL19082926

SCHEMBL19082926

CCCc1cc(F)c(OCc2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)cc3)c(F)c2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.37
RARB P10826 1/20 0.37
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
PKM P14618 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
FFAR1 O14842 1/20 0.34
CNR1 P21554 3/20 0.33
MAOB P27338 1/20 0.33
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
CNR2 P34972 2/20 0.33
CHKA P35790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082931 0.94 FFAR4 (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL19082890 0.94 FFAR4 (0.36) FFAR4RARBNPC1TP53PKM
SCHEMBL19082929 0.93 RARB (0.43) FFAR4RARBNPC1RAB9ASMN1; SMN2
SCHEMBL19082921 0.93 FFAR4 (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL19082928 0.92 RARB (0.47) FFAR4RARBNPC1RAB9ASMN1; SMN2
SCHEMBL19082888 0.91 FFAR4 (0.40) FFAR4RARBNPC1TP53PKM
SCHEMBL16038268 0.90 RARB (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL16584722 0.90 RARB (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL19082927 0.90 FFAR4 (0.36) FFAR4RARBFFAR1CNR1MAOB
SCHEMBL19082822 0.88 MAOB (0.38) FFAR4RARBNPC1TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed