SCHEMBL19082822

SCHEMBL19082822

CCCc1ccc(-c2cc(F)c(OCc3cc(F)c(F)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.38
FFAR4 Q5NUL3 5/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
RARB P10826 1/20 0.34
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FFAR1 O14842 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
MAPT P10636 1/20 0.32
PDK2 Q15119 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
ALOX5 P09917 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082890 0.95 FFAR4 (0.36) MAOBFFAR4RARBNPC1TP53
SCHEMBL16038268 0.94 RARB (0.37) MAOBFFAR4RARBNPC1TP53
SCHEMBL19082931 0.92 FFAR4 (0.37) MAOBFFAR4RARBNPC1TP53
SCHEMBL19082825 0.92 RARB (0.40) MAOBFFAR4RARBNPC1TP53
SCHEMBL19082829 0.91 RARB (0.44) MAOBFFAR4RARBTP53HSD17B10
SCHEMBL19082921 0.91 FFAR4 (0.37) MAOBFFAR4RARBNPC1TP53
SCHEMBL17487942 0.90 CTSL (0.35) MAOBFFAR4RARBGABRA1GABRB2
SCHEMBL19082849 0.89 MAOB (0.40) MAOBFFAR4NPC1RAB9ASMN1; SMN2
SCHEMBL16584722 0.88 RARB (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL19082926 0.88 FFAR4 (0.37) MAOBFFAR4CNR1CNR2RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed