SCHEMBL19082931

SCHEMBL19082931

CCCc1cc(F)c(OCc2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 10/20 0.37
RARB P10826 1/20 0.35
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
PKM P14618 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
FFAR1 O14842 2/20 0.34
MAOB P27338 1/20 0.34
FEN1 P39748 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082890 0.97 FFAR4 (0.36) FFAR4RARBNPC1TP53PKM
SCHEMBL19082921 0.94 FFAR4 (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL19082926 0.94 FFAR4 (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL19082933 0.93 RARB (0.41) FFAR4RARBNPC1RAB9ASMN1; SMN2
SCHEMBL19082822 0.92 MAOB (0.38) FFAR4RARBNPC1TP53PKM
SCHEMBL19082932 0.91 RARB (0.46) FFAR4RARBNPC1TP53RAB9A
SCHEMBL16038268 0.91 RARB (0.37) FFAR4RARBNPC1TP53PKM
SCHEMBL19082887 0.90 RARB (0.40) FFAR4RARBNPC1TP53RAB9A
SCHEMBL19082930 0.90 FFAR4 (0.36) FFAR4FFAR1MAOBFEN1
SCHEMBL16584722 0.89 RARB (0.37) FFAR4RARBNPC1TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed