SCHEMBL19082932

SCHEMBL19082932

CCCCCc1cc(F)c(OCc2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.46
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40
FFAR4 Q5NUL3 2/20 0.36
PTGS2 P35354 5/20 0.35
FAAH O00519 1/20 0.35
CYP3A4 P08684 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
STAT3 P40763 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
ESR1 P03372 2/20 0.33
ADRA2A P08913 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
TACR2 P21452 2/20 0.33
SLC6A2 P23975 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082886 0.98 RARB (0.44) RARBRARARARGFFAR4PTGS2
SCHEMBL19082933 0.96 RARB (0.41) RARBRARARARGFFAR4PTGS2
SCHEMBL19082924 0.94 RARB (0.45) RARBRARARARGFFAR4PTGS2
SCHEMBL19082928 0.94 RARB (0.47) RARBRARARARGFFAR4PTGS2
SCHEMBL19082887 0.94 RARB (0.40) RARBRARARARGFFAR4PTGS2
SCHEMBL19082829 0.93 RARB (0.44) RARBRARARARGFFAR4PTGS2
SCHEMBL19082870 0.92 RARB (0.47) RARBRARARARGPTGS2CYP3A4
SCHEMBL19082931 0.91 FFAR4 (0.37) RARBFFAR4RAB9ANPC1SMN1; SMN2
SCHEMBL19082923 0.91 RARB (0.40) RARBRARARARGFFAR4RAB9A
SCHEMBL19082929 0.91 RARB (0.43) RARBRARARARGFFAR4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed