Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.54 |
| ▸ | LMNA | P02545 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119352 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL19064634 | 0.81 | POLB (0.65) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL19082963 | 0.80 | NPY5R (0.49) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL20119913 | 0.78 | POLB (0.66) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL16146496 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL19082962 | 0.78 | CLK2 (0.39) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| Rolodine SCHEMBL121916 | 0.78 | NPY5R (0.49) | SMN1; SMN2LMNAALDH1A1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL22346221 | 0.77 | POLB (0.64) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL19082946 | 0.77 | ADORA2A (0.40) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL22224126 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190704-A1 | COMPOSITIONS AND METHODS USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | Mitokinin, LLC (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190704-A1 | COMPOSITIONS AND METHODS USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | NLN, HAGH, MT-ND2 | SMN1; SMN2 87/4885LMNA 1132/4885HTT 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.