Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907532 | 0.88 | KMT2A (0.33) | KMT2A | |
| SCHEMBL12095371 | 0.83 | AKT1 (0.34) | EGFRMEN1KMT2A | |
| SCHEMBL1900766 | 0.78 | IP6K1 (0.38) | MEN1KMT2A | |
| SCHEMBL1908352 | 0.77 | AKT1 (0.41) | EGFR | |
| SCHEMBL1905670 | 0.76 | AKT1 (0.47) | — | |
| SCHEMBL14118927 | 0.75 | TACR3 (0.37) | EGFRMEN1KMT2A | |
| SCHEMBL14118930 | 0.75 | TACR3 (0.37) | EGFRMEN1KMT2A | |
| SCHEMBL1899965 | 0.71 | IDO1 (0.35) | — | |
| SCHEMBL1904895 | 0.69 | AKT1 (0.36) | KMT2A | |
| SCHEMBL3709808 | 0.67 | AKT1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055115-A1 | AKT / PKB INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |