Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901170 | 0.81 | IP6K1 (0.43) | IP6K1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1907532 | 0.81 | KMT2A (0.33) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL1908351 | 0.78 | EGFR (0.32) | KMT2AMEN1 | |
| SCHEMBL1904736 | 0.77 | AKT1 (0.51) | IP6K1RAB9AAKT1AKT2 | |
| SCHEMBL1900768 | 0.76 | AKT1 (0.42) | IP6K1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL14119098 | 0.74 | IP6K1 (0.43) | IP6K1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1901016 | 0.69 | AKT1 (0.51) | IP6K1AKT1AKT2 | |
| SCHEMBL1908498 | 0.69 | IP6K1 (0.35) | IP6K1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1900928 | 0.69 | RAB9A (0.36) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| Carbamic Acid SCHEMBL1908497 | 0.68 | IP6K1 (0.37) | IP6K1KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055115-A1 | AKT / PKB INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |