SCHEMBL19083669

SCHEMBL19083669

CN1CCC(=O)N(I)C(=O)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
BRD4 O60885 1/20 0.39
BRD2 P25440 1/20 0.39
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
DRD2 P14416 1/20 0.34
DRD1 P21728 1/20 0.34
DRD4 P21917 1/20 0.34
DRD5 P21918 1/20 0.34
DRD3 P35462 1/20 0.34
NOS1 P29475 1/20 0.33
ACHE P22303 1/20 0.32
SETD7 Q8WTS6 1/20 0.31
POLB P06746 1/20 0.31
CRBN Q96SW2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17324575 0.83 GAA (0.42) GAABRD4BRD2NPC1RAB9A
SCHEMBL19112764 0.80 GAA (0.42) GAABRD4BRD2NPC1RAB9A
SCHEMBL1058967 0.76
SCHEMBL18779 0.76
SCHEMBL12022454 0.74 BRD4 (0.56) GAABRD4BRD2NPC1RAB9A
Iodide SCHEMBL2789427 0.74
Hydrogen Sulfide SCHEMBL15467095 0.74
SCHEMBL30271302 0.74
SCHEMBL23430212 0.71 BRD4 (0.39) BRD4BRD2L3MBTL1KMT2A
SCHEMBL11114696 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170190674-A1 Unique Self-Assembled Poly-Amidoamine Polymers and Their Electrochemical Reactivity ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170190674-A1 Unique Self-Assembled Poly-Amidoamine Polymers and Their Electrochemical Reactivity PAM, FAM83A, EPM2A GAA 1652/4885BRD4 4252/4885BRD2 4314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.