SCHEMBL19083849

SCHEMBL19083849

CCCC(=O)NCCC[Si](OC)(OC)OC

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 0.58
TSHR P16473 1/20 0.47
NAAA Q02083 1/20 0.46
FAAH O00519 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29189002 0.96 CASP2 (0.55) CASP2TSHRNAAASMN1; SMN2
SCHEMBL25801633 0.91 CASP2 (0.52) CASP2TSHRNAAAFAAH
SCHEMBL22174072 0.90 TSHR (0.52) CASP2TSHRNAAAFAAH
SCHEMBL18164189 0.89 TSHR (0.55) CASP2TSHRNAAAFAAH
SCHEMBL5664870 0.88 FAAH (0.60) CASP2NAAAFAAH
SCHEMBL29105414 0.88 FAAH (0.60) CASP2NAAAFAAH
SCHEMBL31074228 0.88 FAAH (0.60) CASP2NAAAFAAH
SCHEMBL30763456 0.88 FAAH (0.60) CASP2NAAAFAAH
SCHEMBL27805033 0.87 CASP2 (0.52) CASP2TSHRNAAAFAAH
SCHEMBL19092416 0.87 CASP2 (0.49) CASP2TSHRNAAAFAAHSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221942-A Heteroatom modified silicon resin and preparation method of high-temperature-resistant adhesive thereof 哈尔滨工业大学 2024-06-21 CN disclosed
US-11696959-B2 Nanoparticle-cell construct with platinum anti-cancer agent CITY OF HOPE (US) 2023-07-11 US disclosed
WO-2018144954-A1 SILICA NANOPARTICLE WITH AN INSOLUBLE DRUG CITY OF HOPE (US) 2018-08-09 WO disclosed
WO-2017117275-A1 SILICA NANOPARTICLE WITH PLATINUM ANTI-CANCER AGENT CITY OF HOPE (US) 2017-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696959-B2 Nanoparticle-cell construct with platinum anti-cancer agent CD47, TP53, CD63 CASP2 783/4885TSHR 4222/4885NAAA 3354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.