Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 9/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908954 | 0.87 | SCN9A (0.43) | SCN9ARORCALDH1A1DCUN1D1PKM | |
| SCHEMBL20697640 | 0.85 | SCN9A (0.42) | SCN9ARORCDCUN1D1PKMPKLR | |
| SCHEMBL19075810 | 0.84 | OPRM1 (0.38) | RORCMGAT2ALDH1A1DRD2DRD4 | |
| SCHEMBL19075643 | 0.84 | RORC (0.42) | SCN9ARORCALDH1A1DCUN1D1PKM | |
| SCHEMBL19083787 | 0.79 | DCUN1D1 (0.43) | MGAT2DCUN1D1DRD2BCHEACHE | |
| SCHEMBL19083688 | 0.78 | SCN9A (0.47) | SCN9ARORCALDH1A1PKMPKLR | |
| SCHEMBL19427314 | 0.77 | SCN9A (0.50) | SCN9ARORCALDH1A1PKMPKLR | |
| SCHEMBL19075613 | 0.76 | MGAT2 (0.45) | MGAT2ALDH1A1GAADCUN1D1BCHE | |
| SCHEMBL19075547 | 0.76 | ACKR3 (0.45) | MGAT2ALDH1A1DRD2DRD4 | |
| SCHEMBL21075511 | 0.75 | SCN9A (0.45) | SCN9AALDH1A1PKMPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190662-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190662-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | RDX, C1R, MTX1 | SCN9A 2337/4885RORC 717/4885MGAT2 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.