Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089217 | 0.84 | GAA (0.50) | GAAEPHX1NFKB1NFKB2RELA | |
| SCHEMBL19099041 | 0.84 | GAA (0.46) | GAAEPHX1NFKB1NFKB2RELA | |
| SCHEMBL17898784 | 0.82 | GAA (0.44) | GAAEPHX1NFKB1NFKB2RELA | |
| SCHEMBL19099471 | 0.82 | GAA (0.44) | GAAEPHX1NFKB1NFKB2RELA | |
| SCHEMBL19084175 | 0.81 | GAA (0.43) | GAAEPHX1NFKB1NFKB2RELA | |
| SCHEMBL19824266 | 0.78 | GAA (0.51) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL19084177 | 0.78 | GAA (0.41) | GAAEPHX1NFKB1NFKB2RELA | |
| SCHEMBL19084159 | 0.77 | NAAA (0.41) | GAANAAA | |
| SCHEMBL19099668 | 0.77 | GAA (0.40) | GAAEPHX1NFKB1NFKB2RELA | |
| SCHEMBL19066617 | 0.77 | GAA (0.40) | GAAEPHX1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116956-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017116939-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |