Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19084187 | 0.84 | GAA (0.48) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL19091088 | 0.81 | GAA (0.49) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL17898858 | 0.80 | GAA (0.41) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL19091547 | 0.80 | GAA (0.47) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL19089218 | 0.79 | GAA (0.46) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL19091104 | 0.78 | GAA (0.44) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL19089222 | 0.78 | GAA (0.45) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL17428283 | 0.77 | GAA (0.47) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL6885957 | 0.77 | GAA (0.58) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL2314003 | 0.77 | GAA (0.58) | GAACTSDBTKNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017116954-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |