SCHEMBL19084269

SCHEMBL19084269

CCCCC1(C)c2ccccc2Cc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.61
ALOX12 P18054 1/20 0.42
SIGMAR1 Q99720 9/20 0.39
EBP Q15125 1/20 0.37
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
DRD2 P14416 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
SLC6A4 P31645 1/20 0.36
OPRM1 P35372 1/20 0.35
OPRL1 P41146 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19084264 0.89 HTR2A (0.66) HTR2AALOX12SIGMAR1CHRM2ADRA2A
SCHEMBL27686527 0.79 ALOX12 (0.41) HTR2AALOX12ALDH1A1CYP1A2CYP2D6
SCHEMBL28167584 0.78 HTR2A (0.47) HTR2AALOX12SIGMAR1EBPALDH1A1
SCHEMBL20879871 0.74 KMT2A (0.36) HTR2AALOX12ALDH1A1CYP2C19OPRM1
SCHEMBL6060800 0.72 PDK2 (0.40) ALOX12ALDH1A1CYP2C19
SCHEMBL6060767 0.72 PDK2 (0.40) ALOX12ALDH1A1CYP2C19
SCHEMBL14735970 0.72 PDK2 (0.40) ALOX12ALDH1A1CYP2C19
SCHEMBL6060780 0.72 PDK2 (0.40) ALOX12ALDH1A1CYP2C19
SCHEMBL8598177 0.72 PDK2 (0.40) ALOX12ALDH1A1CYP2C19
SCHEMBL6060722 0.72 PDK2 (0.40) ALOX12ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017115978-A1 ORGANIC FILM COMPOSITION AND PATTERN FORMING METHOD 삼성에스디아이 주식회사 2017-07-06 WO disclosed