Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060800 | 1.00 | PDK2 (0.40) | PDK2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL14735970 | 1.00 | PDK2 (0.40) | PDK2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8598177 | 1.00 | PDK2 (0.40) | PDK2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL6060780 | 1.00 | PDK2 (0.40) | PDK2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL6060767 | 1.00 | PDK2 (0.40) | PDK2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL27686527 | 0.92 | ALOX12 (0.41) | PDK2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL15681098 | 0.84 | S100A4 (0.43) | MEN1KMT2ACYP2C9CYP2C19RECQL | |
| SCHEMBL22870080 | 0.84 | PGR (0.40) | PDK2TDP1ALDH1A1 | |
| SCHEMBL12841637 | 0.83 | MEN1 (0.35) | PDK2MEN1KMT2ACYP2C9CYP2C19 | |
| Acrylic Acid SCHEMBL27971917 | 0.83 | CDC25A (0.40) | TDP1MMP2MMP9CDC25AMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298117-B1 | Method for preparing bromofluorenes | JFE CHEMICAL CORP (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-6858764-B2 | Method for preparing bromofluorenes | JFE CHEMICAL CORPORATION (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030065226-A1 | Method for preparing bromofluorenes | ADCHEMCO CORPORATION (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1298117-A2 | Method for preparing bromofluorenes | Adchemco Corporation (JP) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065226-A1 | Method for preparing bromofluorenes | FLNB, AFF2, BRPF1 | PDK2 2076/4885MEN1 1125/4885KMT2A 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.