Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARF6 | P62330 | 14/20 | 0.55 |
| ▸ | PSD | A5PKW4 | 3/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13516748 | 0.90 | ARF6 (0.60) | ARF6PSD | |
| SCHEMBL19084588 | 0.88 | PSD (0.54) | ARF6PSD | |
| SCHEMBL13739694 | 0.86 | ARF6 (0.47) | ARF6PSDCDC7 | |
| SCHEMBL14212972 | 0.86 | ARF6 (0.56) | ARF6PSD | |
| SCHEMBL14234865 | 0.86 | ARF6 (0.56) | ARF6PSD | |
| SCHEMBL19084601 | 0.84 | ARF6 (0.54) | ARF6PSD | |
| SCHEMBL13516568 | 0.84 | ARF6 (0.50) | ARF6PSD | |
| SCHEMBL13516218 | 0.83 | ARF6 (0.65) | ARF6PSD | |
| SCHEMBL19084551 | 0.81 | ARF6 (0.61) | ARF6PSD | |
| SCHEMBL14212971 | 0.80 | ARF6 (0.48) | ARF6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10849901-B2 | Arf6 inhibitors and methods of synthesis and use thereof | NAVIGEN, INC. (US) | 2020-12-01 | — | — | US | disclosed |
| US-20170189405-A1 | ARF6 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF | NAVIGEN, INC. (US) | 2017-07-06 | — | — | US | disclosed |
| US-20170189405-A1 | ARF6 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF | NAVIGEN, INC. (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189405-A1 | ARF6 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF | ARF6, ARF1, ARFIP2 | ARF6 1/4885PSD 211/4885FYN 3103/4885 |
| US-10849901-B2 | Arf6 inhibitors and methods of synthesis and use thereof | ARF6, ARF1, ARFIP2 | ARF6 1/4885PSD 211/4885FYN 3103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.