Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CCNC | P24863 | 3/20 | 0.50 |
| ▸ | CDK8 | P49336 | 3/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19084338 | 0.96 | CCNC (0.53) | MAPTLMNAL3MBTL1CCNCCDK8 | |
| SCHEMBL19085372 | 0.91 | CCNC (0.49) | MAPTLMNAMAPK1CCNCCDK8 | |
| SCHEMBL19281449 | 0.85 | CCNC (0.60) | MAPTLMNAL3MBTL1CCNCCDK8 | |
| SCHEMBL12355077 | 0.84 | KMT2A (0.61) | MAPTLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL15233903 | 0.82 | LMNA (0.48) | MAPTLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL17502603 | 0.82 | LMNA (0.50) | MAPTLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL17502636 | 0.81 | ESR1 (0.56) | MAPTLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL8330145 | 0.81 | KMT2A (0.68) | MAPTLMNAMAPK1L3MBTL1CCNC | |
| SCHEMBL31321713 | 0.80 | HPGD (0.58) | MAPTLMNAMAPK1L3MBTL1CCNC | |
| SCHEMBL19084337 | 0.80 | ESR1 (0.62) | MAPTLMNAL3MBTL1PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117443-A1 | NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS | BRASKEM AMERICA, INC. (US) | 2017-07-06 | — | — | WO | disclosed |