SCHEMBL19085372

SCHEMBL19085372

CCOc1ccc(C(=O)Oc2cccc3cccc(OC(=O)c4ccc(O)cc4)c23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNC P24863 2/20 0.49
CDK8 P49336 2/20 0.49
KMT2A Q03164 4/20 0.47
MAOB P27338 1/20 0.47
ABCG2 Q9UNQ0 1/20 0.47
LTA4H P09960 1/20 0.46
PDGFRB P09619 1/20 0.46
PDGFRA P16234 1/20 0.46
ESR1 P03372 3/20 0.45
ESR2 Q92731 3/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
NPC1 O15118 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
PAX8 Q06710 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19084338 0.95 CCNC (0.53) CCNCCDK8KMT2APDGFRBPDGFRA
SCHEMBL19085330 0.91 MAPT (0.52) CCNCCDK8KMT2AMAOBPDGFRB
SCHEMBL19281449 0.81 CCNC (0.60) CCNCCDK8KMT2AMAOBPDGFRB
SCHEMBL27250364 0.81 KMT2A (0.66) CCNCCDK8KMT2AMAOBABCG2
SCHEMBL10624035 0.81 KMT2A (0.66) CCNCCDK8KMT2AMAOBABCG2
SCHEMBL19084337 0.79 ESR1 (0.62) KMT2APDGFRBPDGFRAESR1ESR2
SCHEMBL26039871 0.78 MAPT (0.58) CCNCCDK8KMT2AMAOBABCG2
SCHEMBL31321713 0.76 HPGD (0.58) CCNCCDK8KMT2ANPC1PKM
SCHEMBL20646378 0.75 ESR1 (0.60) KMT2AESR1ESR2LMNAALDH1A1
SCHEMBL5706089 0.75 L3MBTL1 (0.55) CCNCCDK8KMT2AMAOBPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11117982-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2021-09-14 US disclosed
US-11041028-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2021-06-22 US disclosed
US-20200199262-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. 2020-06-25 US disclosed
US-10633463-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2020-04-28 US disclosed
US-20190016832-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2019-01-17 US disclosed
WO-2017117443-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2017-07-06 WO disclosed