Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704549 | 0.86 | — | — | |
| SCHEMBL18154865 | 0.82 | THRB (0.35) | CYP1A2MAPK1SMN1; SMN2SIGMAR1HRH3 | |
| SCHEMBL1535860 | 0.82 | THRB (0.35) | CYP1A2MAPK1SMN1; SMN2SIGMAR1HRH3 | |
| SCHEMBL26498896 | 0.81 | HRH3 (0.39) | CYP1A2MAPK1SMN1; SMN2SLC22A6TSHR | |
| Ethylene Glycol SCHEMBL672311 | 0.81 | THRB (0.36) | CYP1A2SIGMAR1HRH3GPR84ALDH1A1 | |
| SCHEMBL1861972 | 0.79 | HRH3 (0.62) | CYP1A2MAPK1SMN1; SMN2HRH3 | |
| SCHEMBL1858200 | 0.79 | HRH3 (0.62) | CYP1A2MAPK1SMN1; SMN2HRH3 | |
| SCHEMBL1856917 | 0.79 | HRH3 (0.62) | CYP1A2MAPK1SMN1; SMN2HRH3 | |
| SCHEMBL31530011 | 0.79 | KDM5A (0.40) | SIGMAR1HRH3 | |
| SCHEMBL20590547 | 0.78 | THRB (0.35) | CYP1A2SIGMAR1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117528-A1 | LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | Acuitas Therapeutics, Inc. (CA) | 2017-07-06 | — | — | WO | disclosed |