Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535860 | 1.00 | THRB (0.35) | THRBTHRACYP1A2SMN1; SMN2HRH3 | |
| SCHEMBL30190455 | 0.93 | THRB (0.36) | THRBTHRAHRH3MAPK1ALDH1A1 | |
| SCHEMBL181262 | 0.93 | THRB (0.36) | THRBTHRAHRH3MAPK1ALDH1A1 | |
| SCHEMBL2704549 | 0.90 | — | — | |
| SCHEMBL673452 | 0.89 | THRB (0.33) | THRBTHRACYP1A2SMN1; SMN2HRH3 | |
| Ethylene Glycol SCHEMBL672311 | 0.88 | THRB (0.36) | THRBTHRACYP1A2HRH3ALDH1A1 | |
| Aziridine SCHEMBL11905310 | 0.87 | THRB (0.33) | THRBTHRACYP1A2ALDH1A1 | |
| Propane SCHEMBL1998876 | 0.86 | THRB (0.40) | THRBTHRACYP1A2HRH3ALDH1A1 | |
| SCHEMBL5532392 | 0.83 | THRB (0.37) | THRBTHRACYP1A2HRH3ALDH1A1 | |
| SCHEMBL19085520 | 0.82 | CYP1A2 (0.45) | CYP1A2SMN1; SMN2HRH3MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3757094-A1 | AMIDINE CATALYST FOR CURABLE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2020-12-30 | — | — | EP | disclosed |
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3310763-B1 | AMIDINE CATALYST FOR CURABLE COMPOSITIONS | SIKA TECH AG (CH) | 2020-11-18 | — | — | EP | disclosed |
| EP-3310763-A1 | AMIDINE CATALYST FOR CURABLE COMPOSITIONS | Sika Technology AG (CH) | 2018-04-25 | — | — | EP | disclosed |
| EP-3283550-A1 | AMIDINE-GROUP CONTAINING CATALYST | Sika Technology AG (CH) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016207156-A1 | AMIDINE CATALYST FOR CURABLE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2016-12-29 | — | — | WO | disclosed |
| WO-2016166336-A1 | AMIDINE-GROUP CONTAINING CATALYST | SIKA TECHNOLOGY AG (CH) | 2016-10-20 | — | — | WO | disclosed |