Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 12/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086983 | 0.87 | TMEM97 (0.53) | TMEM97SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL3441575 | 0.82 | TMEM97 (0.52) | TMEM97SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL19086176 | 0.81 | KDM1A (0.51) | PRMT5WDR77MEN1ALDH1A1KMT2A | |
| SCHEMBL19086175 | 0.78 | HDAC6 (0.47) | PRMT5WDR77MEN1ALDH1A1KMT2A | |
| SCHEMBL11175834 | 0.77 | TMEM97 (0.53) | TMEM97SIGMAR1ALDH1A1HPGDHTR1A | |
| SCHEMBL19086350 | 0.76 | MAPT (0.48) | PRMT5WDR77MEN1ALDH1A1KMT2A | |
| SCHEMBL11173780 | 0.75 | TMEM97 (0.48) | TMEM97SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL324228 | 0.73 | TMEM97 (0.67) | TMEM97SIGMAR1PRMT5WDR77MEN1 | |
| SCHEMBL28523456 | 0.73 | HDAC6 (0.53) | PRMT5WDR77MEN1ALDH1A1KMT2A | |
| SCHEMBL28523454 | 0.73 | HDAC6 (0.53) | PRMT5WDR77MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114275-A1 | COMPOUND FOR INHIBITING ROCK, PREPARATION METHOD AND USE OF SAME | 成都先导药物开发有限公司 | 2017-07-06 | — | — | WO | disclosed |