Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 17/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 16/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 16/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 16/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 16/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 16/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 16/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037196 | 0.86 | ALOX5 (0.53) | ALOX5DRD2DRD4DRD3HDAC8 | |
| SCHEMBL5287307 | 0.84 | HDAC8 (0.61) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL15590034 | 0.84 | ALOX5 (0.57) | ALOX5DRD2DRD4DRD3 | |
| SCHEMBL29966213 | 0.84 | L3MBTL1 (0.47) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL16068165 | 0.82 | TEK (0.53) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL29966218 | 0.81 | L3MBTL1 (0.54) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL18373097 | 0.81 | HDAC8 (0.59) | ALOX5HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL19723347 | 0.81 | ALOX5 (0.60) | ALOX5DRD2DRD4DRD3HDAC8 | |
| SCHEMBL20988741 | 0.81 | ALOX5 (0.51) | ALOX5DRD2DRD4DRD3 | |
| SCHEMBL17482382 | 0.80 | MAPK14 (0.50) | ALOX5DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017118690-A1 | A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2017-07-13 | — | — | WO | disclosed |
| EP-3190122-A1 | A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF | LEK Pharmaceuticals d.d. (SI) | 2017-07-12 | — | — | EP | disclosed |