Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoroimide SCHEMBL68964 | 0.78 | MGLL (0.56) | GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL56650 | 0.73 | CA1 (0.58) | MEN1KMT2AKDM4EALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL21326160 | 0.71 | CA1 (0.56) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL3818860 | 0.71 | CA1 (0.64) | MEN1KMT2ATSHREGFRERBB2 | |
| SCHEMBL2488181 | 0.71 | ALDH1A1 (0.59) | MAPTGAAMAPK1L3MBTL1MEN1 | |
| Fluoroimide SCHEMBL4425919 | 0.67 | ALDH1A1 (0.47) | MAPTL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL24360883 | 0.66 | CA1 (0.57) | GAAMEN1KMT2ATSHREGFR | |
| SCHEMBL448847 | 0.66 | KMT2A (0.64) | GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11644411 | 0.65 | CA1 (0.74) | ALDH1A1 | |
| SCHEMBL15437728 | 0.65 | RAD51 (0.49) | MAPTGAAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017118690-A1 | A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2017-07-13 | — | — | WO | disclosed |
| EP-3190122-A1 | A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF | LEK Pharmaceuticals d.d. (SI) | 2017-07-12 | — | — | EP | disclosed |