SCHEMBL19086385

SCHEMBL19086385

COC(=O)Cc1ccc(OC(=O)CCCBr)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.59
ALDH1A1 P00352 3/20 0.59
HTT P42858 2/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
HSD17B10 Q99714 1/20 0.59
LIPE Q05469 1/20 0.51
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
EPHX2 P34913 2/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
MMP9 P14780 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19470857 0.92 KMT2A (0.61) KMT2AALDH1A1HTTLMNAMAPT
SCHEMBL3985473 0.83 SMN1; SMN2 (0.53) KMT2AALDH1A1HTTLMNAMAPT
SCHEMBL9813443 0.80 CYP4A11 (0.66) KMT2AALDH1A1LMNAMAPTHSD17B10
SCHEMBL12227850 0.79 KMT2A (0.70) KMT2AALDH1A1HTTLMNAMAPT
SCHEMBL20766413 0.79 KMT2A (0.55) KMT2AALDH1A1HTTLMNAMAPT
SCHEMBL4406559 0.78 CYP4F2 (0.58) KMT2AALDH1A1HTTLMNAMAPT
SCHEMBL2437986 0.78 ALDH1A1 (0.54) KMT2AALDH1A1HTTLMNAMAPT
SCHEMBL4113212 0.77 CYP4F2 (0.76) KMT2AALDH1A1HTTLMNAMAPT
SCHEMBL6288240 0.77 ALDH1A1 (0.56) KMT2AALDH1A1HTTLIPECYP4F2
SCHEMBL8158284 0.76 CYP4F2 (0.70) KMT2AALDH1A1LMNAMAPTCYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3190131-B1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER UNIV KYOTO (JP) 2020-07-29 EP disclosed
US-10414848-B2 Living radical polymerization initiator, method for producing polymer, and polymer KYOTO UNIVERSITY (JP) 2019-09-17 US disclosed
US-20170306073-A1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER KYOTO UNIVERSITY (JP) 2017-10-26 US disclosed
EP-3190131-A1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER Kyoto University (JP) 2017-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10414848-B2 Living radical polymerization initiator, method for producing polymer, and polymer CCNY, MTR, PARN KMT2A 453/4885ALDH1A1 2596/4885HTT 1859/4885
US-20170306073-A1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER CCNY, MTR, PARN KMT2A 453/4885ALDH1A1 2596/4885HTT 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.