Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911725 | 0.78 | RAB9A (0.60) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL4790790 | 0.77 | NPC1 (0.55) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL3486359 | 0.75 | PIK3CG (0.60) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL433724 | 0.75 | RAB9A (0.56) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL12778714 | 0.75 | RAB9A (0.56) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL16087132 | 0.75 | APP (0.46) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL286467 | 0.72 | KDM4E (0.65) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL1691409 | 0.72 | RAB9A (1.00) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL9598420 | 0.71 | KDM4E (0.63) | RAB9ANPC1KDM4ETP53ALDH1A1 | |
| SCHEMBL8812209 | 0.71 | SCN5A (0.53) | RAB9ANPC1KDM4ETP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |