SCHEMBL19087101

SCHEMBL19087101

COc1ccc(Cc2ccc(-c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.62
LTA4H P09960 2/20 0.61
MAPT P10636 2/20 0.58
MAPK1 P28482 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
ALOX5 P09917 2/20 0.56
MAOB P27338 2/20 0.55
IDH1 O75874 1/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP17A1 P05093 1/20 0.51
MEN1 O00255 1/20 0.51
RELA Q04206 1/20 0.50
EDNRA P25101 1/20 0.49
SAE1 Q9UBE0 1/20 0.49
UBA2 Q9UBT2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14030856 1.00 ACHE (0.62) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL13020521 0.94 ACHE (0.56) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL13020514 0.94 ACHE (0.56) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL13801587 0.94 ACHE (0.56) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL14826542 0.94 ACHE (0.56) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL13020525 0.94 ACHE (0.56) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL13508238 0.94 ACHE (0.56) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL13020524 0.94 ACHE (0.56) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL3409810 0.94 ACHE (0.71) ACHELTA4HMAPTMAPK1L3MBTL1
SCHEMBL22451382 0.91 LTA4H (0.71) LTA4HMAOBIDH1CYP17A1SAE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE48156-E1 Electronic device comprising an organic semiconducting material NOVALED GMBH (DE) 2020-08-11 US disclosed
US-9923148-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2018-03-20 US disclosed
US-20170194568-A9 Electroluminescent Device UDC IRELAND LIMITED (IE) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194568-A9 Electroluminescent Device DPYD, PNPO, TYMP ACHE 325/4885LTA4H 2774/4885MAPT 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.