SCHEMBL1908797

SCHEMBL1908797

COC(=O)CCCC(C)(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
LMNA P02545 4/20 0.45
ALDH1A1 P00352 2/20 0.45
RECQL P46063 1/20 0.45
KMT2A Q03164 4/20 0.41
MEN1 O00255 2/20 0.41
CA12 O43570 2/20 0.40
CA14 Q9ULX7 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
PTPRB P23467 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27984675 0.98 TSHR (0.61) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL1909002 0.93 TSHR (0.61) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL10611084 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL22712309 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL12933269 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL24383921 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL1478447 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL2254876 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL27507029 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A
SCHEMBL2935590 0.91 TSHR (0.58) TSHRLMNAALDH1A1RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230223869-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2023-07-13 US claimed
CN-118667899-A Longan insoluble dietary fiber with slow glycolysis characteristic, and preparation method and application thereof 华南农业大学 2024-09-20 CN disclosed
EP-4234014-A1 AMINO ACID BASED CARBAMATES AND/OR UREAS FOR THE TREATMENT OF SORTILIN DEPENDENT DISEASES Insusense ApS (DK) 2023-08-30 EP disclosed
US-11724980-B2 Quinones having high capacity retention for use as electrolytes in aqueous redox flow batteries PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-08-15 US disclosed
US-20230223869-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2023-07-13 US disclosed
CN-109952360-B Quantum dot dispersion, self-luminous photosensitive resin composition, color filter manufactured using the same, and image display device 东友精细化工有限公司 2022-03-22 CN disclosed
CN-109810589-A Light converts resin combination, light conversion layer folds substrate and image display device 东友精细化工有限公司 2019-05-28 CN disclosed
US-20190151403-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF S&T GLOBAL INC. 2019-05-23 US disclosed
US-20180147289-A9 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers SYNTARGA BV (NL) 2018-05-31 US disclosed
US-20180133316-A9 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers SYNTARGA BV (NL) 2018-05-17 US disclosed
US-7868205-B2 Inhibitors of histone deacetylase METHYLGENE INC. (CA) 2011-01-11 US disclosed
US-20090253908-A1 NOVEL M3 MUSCARINIC ACETYLCHOINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED 2009-10-08 US disclosed
US-20080221179-A1 SUBSTITUTED PHENOXY AMINOTHIAZOLONES as estrogen related receptor-alpha modulators JANSSEN PHARMACEUTICA N.V. (BE) 2008-09-11 US disclosed
US-20080221179-A1 SUBSTITUTED PHENOXY AMINOTHIAZOLONES as estrogen related receptor-alpha modulators JANSSEN PHARMACEUTICA N.V. (BE) 2008-09-11 US disclosed
US-20080132459-A1 Inhibitors of Histone Deacetylase METHYLGENE, INC. (CA) 2008-06-05 US disclosed
US-20080132459-A1 Inhibitors of Histone Deacetylase METHYLGENE, INC. (CA) 2008-06-05 US disclosed
US-20070213315-A1 Modulators of muscarinic receptors VERTEX PHARMACEUTICALS INCORPORATED 2007-09-13 US disclosed
US-20070213315-A1 Modulators of muscarinic receptors VERTEX PHARMACEUTICALS INCORPORATED 2007-09-13 US disclosed
US-6107523-A WATER INSOLUBLE BETA-DIKETONE COPPER EXTRACTANT DISSOLVED IN A WATER-IMMISCIBLE ORGANIC SOLVENT TO EXTRACT COPPER VALUES HENKEL CORPORATION (US) 2000-08-22 US disclosed
US-5936129-A PREVENTING BY-PRODUCT PRODUCTION OF CHEMICAL CONDENSATION REACTION, REACTING A HINDERED ALIPHATIC ESTER AND A KETONE IN PRESENCE OF A STRONG BASE AND A SOLVENT, REACTING THE FORMED SOLUTION WITH THE KETONE HENKEL CORPORATION (US) 1999-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213315-A1 Modulators of muscarinic receptors CHRM3, CHRM5, CHRM2 TSHR 131/4885LMNA 4093/4885ALDH1A1 2356/4885
US-20080132459-A1 Inhibitors of Histone Deacetylase HDAC1, HDAC5, HDAC3 TSHR 3869/4885LMNA 1922/4885ALDH1A1 796/4885
US-20190151403-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF MALT1, MYLK2, FKBP1B TSHR 4178/4885LMNA 3053/4885ALDH1A1 2805/4885
US-20180133316-A9 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers PCNA, DCLRE1A, CDC5L TSHR 2473/4885LMNA 2614/4885ALDH1A1 2514/4885
US-20080221179-A1 SUBSTITUTED PHENOXY AMINOTHIAZOLONES as estrogen related receptor-alpha modulators ESR2, ESRRA, ESRRG TSHR 1315/4885LMNA 3434/4885ALDH1A1 2518/4885
US-20180147289-A9 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers PCNA, DCLRE1A, CDC5L TSHR 2473/4885LMNA 2614/4885ALDH1A1 2514/4885
US-11724980-B2 Quinones having high capacity retention for use as electrolytes in aqueous redox flow batteries NQO1, NDUFS5, NDUFS2 TSHR 4722/4885LMNA 3998/4885ALDH1A1 210/4885
US-20090253908-A1 NOVEL M3 MUSCARINIC ACETYLCHOINE RECEPTOR ANTAGONISTS CHRM3, CHRM2, CHRNA3 TSHR 206/4885LMNA 4351/4885ALDH1A1 1423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.