Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1788330 | 0.82 | ALDH1A1 (0.46) | MAPK1L3MBTL1TDP1TSHRALDH1A1 | |
| SCHEMBL6666574 | 0.82 | ALDH1A1 (0.46) | MAPK1L3MBTL1TDP1TSHRALDH1A1 | |
| SCHEMBL1788331 | 0.81 | ALDH1A1 (0.48) | MAPK1L3MBTL1TDP1TSHRPTGS2 | |
| SCHEMBL16154053 | 0.81 | ALDH1A1 (0.63) | MAPK1L3MBTL1TDP1TSHRALDH1A1 | |
| SCHEMBL26240902 | 0.80 | ALDH1A1 (0.47) | MAPK1L3MBTL1TDP1ALDH1A1HPGD | |
| SCHEMBL1107604 | 0.80 | ALDH1A1 (0.62) | MAPK1L3MBTL1TDP1TSHRALDH1A1 | |
| SCHEMBL201855 | 0.80 | ALDH1A1 (0.62) | MAPK1L3MBTL1TDP1TSHRALDH1A1 | |
| SCHEMBL320610 | 0.80 | ALDH1A1 (0.62) | MAPK1L3MBTL1TDP1TSHRALDH1A1 | |
| SCHEMBL27433761 | 0.80 | CYP3A4 (0.48) | TSHRALDH1A1 | |
| SCHEMBL6648255 | 0.79 | ALDH1A1 (0.43) | MAPK1L3MBTL1TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |