Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107604 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL201855 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL21688461 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL5400343 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL10165250 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL5400346 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL18651131 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| Valine SCHEMBL28307488 | 0.87 | SLC15A1 (0.58) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL24859302 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL21688727 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720550-A | Synthesis method of (S) -3-methyl-4-oxo-2-oxa-8-azaspiro [4.5] decane-8-carboxylic acid tert-butyl ester | 深圳市华先医药科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| US-20260109711-A1 | MACROCYCLIC SULFONAMIDE MODULATORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2026-04-23 | — | — | US | disclosed |
| US-12577325-B2 | Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof | SYSTIMMUNE, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20250376443-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-12-11 | — | — | US | disclosed |
| US-20250368604-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-12-04 | — | — | US | disclosed |
| US-12478696-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2025-11-25 | — | — | US | disclosed |
| EP-4619048-A1 | CYCLEN BASED COMPOUNDS AND THEIR GD(III) COMPLEXES FOR USE AS MULTIMODAL PET/MRI CONTRAST AGENTS | Ustav Organicke Chemie a Biochemie AV CR v.v.i. (CZ) | 2025-09-24 | — | — | EP | disclosed |
| EP-3676265-B1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-08-20 | — | — | EP | disclosed |
| EP-4595978-A1 | ANTI-CD33 ANTIBODY AND ANTI-CD33 ANTIBODY-DRUG CONJUGATE AND USE THEREOF | SystImmune, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250205349-A1 | ANTI-HUMAN TROP2 ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND MEDICAL USE THEREOF | SYSTIMMUNE, INC. | 2025-06-26 | — | — | US | disclosed |
| US-5002692-A | Amide liquid crystal compounds: mixtures and devices using them | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1991-03-26 | — | — | US | disclosed |
| EP-0258298-B1 | LIQUID CRYSTAL COMPOUNDS CONTAINING TWO OR MORE CHIRAL CENTERS | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOV. OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1990-08-29 | — | — | EP | disclosed |
| US-4923633-A | Liquid crystal compounds containing two or more chiral centers | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1990-05-08 | — | — | US | disclosed |
| EP-0201578-B1 | ALPHA-HYDROXY CARBOXYLIC ACID DERIVATIVES SUITABLE FOR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1989-11-02 | — | — | EP | disclosed |
| US-4852977-A | 19 -hydroxy carboxylic acid derivatives suitable for use in liquid crystal materials and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0301021-A1 | AMIDE LIQUID CRYSTAL COMPOUNDS: MIXTURES AND DEVICES USING THEM. | SECR DEFENCE BRIT (GB) | 1989-02-01 | — | — | EP | disclosed |
| EP-0258298-A1 | LIQUID CRYSTAL COMPOUNDS CONTAINING TWO OR MORE CHIRAL CENTERS. | SECR DEFENCE BRIT (GB) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987005896-A1 | AMIDE LIQUID CRYSTAL COMPOUNDS: MIXTURES AND DEVICES USING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1987-10-08 | — | — | WO | disclosed |
| WO-1987004705-A2 | LIQUID CRYSTAL COMPOUNDS CONTAINING TWO OR MORE CHIRAL CENTERS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1987-08-13 | — | — | WO | disclosed |
| CN-85109025-A | The liquid-crystal composition that contains the alpha-hydroxy carboxylic acid compounds derivative | — | 1986-09-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109711-A1 | MACROCYCLIC SULFONAMIDE MODULATORS | HCRTR2, HCRTR1, CNR1 | ALDH1A1 1750/4885TDP1 4616/4885MAPK1 2000/4885 |
| US-12478696-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | GLRA1, GLRA3, GLRB | ALDH1A1 3811/4885TDP1 1272/4885MAPK1 1678/4885 |
| US-12577325-B2 | Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof | IGLV6-57, EGFR, ERBB2 | ALDH1A1 3799/4885TDP1 1675/4885MAPK1 2880/4885 |
| US-20250368604-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | ALDH1A1 4701/4885TDP1 1427/4885MAPK1 2993/4885 |
| US-20250376443-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | ALDH1A1 4718/4885TDP1 1688/4885MAPK1 3012/4885 |
| US-20250205349-A1 | ANTI-HUMAN TROP2 ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND MEDICAL USE THEREOF | TOP2A, TPM4, TPM3 | ALDH1A1 759/4885TDP1 134/4885MAPK1 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.