SCHEMBL19088567

SCHEMBL19088567

CN[C@@H](CC(C)(C)F)C(=O)O[C@H](Cc1ccc(C2=CCOCC2)cc1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.39
SRR Q9GZT4 2/20 0.36
PSAT1 Q9Y617 2/20 0.36
CTSC P53634 1/20 0.36
PPARG P37231 12/20 0.35
PPARA Q07869 10/20 0.35
PPARD Q03181 1/20 0.34
PTGER4 P35408 1/20 0.34
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19088501 0.90 AAK1 (0.36) AAK1SRRPSAT1CTSCPPARG
SCHEMBL24297805 0.89 AAK1 (0.38) AAK1CTSCPTGER4PIK3CAMTOR
SCHEMBL21266633 0.84 AAK1 (0.35) AAK1PPARAPTGER4PIK3CAMTOR
SCHEMBL19088566 0.81 AAK1 (0.34) AAK1CTSCPPARGPPARAPTGER4
SCHEMBL19088575 0.79 CTSL (0.32) AAK1
SCHEMBL19066783 0.75 CTSC (0.38) AAK1SRRPSAT1CTSCPPARG
SCHEMBL25364300 0.75 CTSC (0.38) AAK1SRRPSAT1CTSCPPARG
SCHEMBL21159528 0.74 CTSL (0.32)
SCHEMBL22502772 0.74 AAK1 (0.35) AAK1CTSCPPARGPPARA
SCHEMBL23279554 0.74 ITGB3 (0.34) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116702-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL, INC. (US) 2017-07-06 WO disclosed