Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256436 | 0.84 | MEN1 (0.48) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL31560871 | 0.84 | MEN1 (0.48) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL19088554 | 0.80 | AOC3 (0.53) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL18248176 | 0.79 | MEN1 (0.47) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL19245059 | 0.77 | AOC3 (0.50) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL23279498 | 0.76 | KDM4E (0.47) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL18256437 | 0.74 | LMNA (0.54) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL19066710 | 0.74 | MEN1 (0.47) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL23279546 | 0.74 | KDM4E (0.45) | MEN1KMT2ANPSR1KDM4EDGAT1 | |
| SCHEMBL21447852 | 0.74 | MEN1 (0.46) | MEN1KMT2ANPSR1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |