Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.30 |
| ▸ | CTSH | P09668 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25183012 | 0.88 | CTSS (0.40) | CTSSCTSKNR1H2AAK1MMP13 | |
| SCHEMBL1337408 | 0.88 | CTSS (0.40) | CTSSCTSKNR1H2AAK1MMP13 | |
| SCHEMBL8269704 | 0.86 | CTSS (0.36) | CTSSCTSKNR1H2AAK1MMP13 | |
| SCHEMBL21266697 | 0.85 | CTSS (0.39) | CTSSCTSKNR1H2AAK1MMP13 | |
| SCHEMBL23519021 | 0.82 | CTSS (0.34) | CTSSCTSKNR1H2AAK1MMP13 | |
| SCHEMBL25185691 | 0.82 | CTSK (0.41) | CTSSCTSKMMP13CTSLCTSB | |
| SCHEMBL19066777 | 0.82 | CTSK (0.39) | CTSSCTSKAAK1MMP13KMT2A | |
| SCHEMBL25179484 | 0.82 | CTSK (0.39) | CTSSCTSKAAK1MMP13KMT2A | |
| SCHEMBL30639521 | 0.82 | CTSK (0.41) | CTSSCTSKMMP13CTSLCTSB | |
| SCHEMBL66693 | 0.81 | CTSK (0.43) | CTSSCTSKMMP13CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |