Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704988 | 0.87 | RECQL (0.50) | POLBALDH1A1RORCKMT2AMAPT | |
| SCHEMBL2350397 | 0.86 | POLB (0.49) | POLBALDH1A1RORCKMT2AMAPT | |
| SCHEMBL11846210 | 0.78 | GABRP (0.53) | ALDH1A1RORCGAAMAPTNPC1 | |
| SCHEMBL2705242 | 0.78 | SMN1; SMN2 (0.59) | POLBALDH1A1GAAMAPTKDM4E | |
| SCHEMBL15473715 | 0.78 | POLB (0.40) | POLBALDH1A1RORCGAAMAPT | |
| SCHEMBL27877492 | 0.78 | CA12 (0.59) | POLBRORCKMT2ANPC1RAB9A | |
| SCHEMBL3218274 | 0.73 | CSF1R (0.43) | POLBRORC | |
| SCHEMBL4119074 | 0.73 | NPC1 (0.47) | ALDH1A1RORCKMT2AMEN1GAA | |
| SCHEMBL4118699 | 0.73 | RECQL (0.46) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1502321 | 0.73 | ALDH1A1 (0.48) | POLBALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017513-B2 | Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido [5,4-D][2]benzazepin-2-YL]amino}-2-methoxybenzoate | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170190706-A1 | CRYSTALLINE FORMS OF SODIUM 4--2-METHOXYBENZOATE | MILLENNIUM PHARMACEUTICALS, INC. | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190706-A1 | CRYSTALLINE FORMS OF SODIUM 4--2-METHOXYBENZOATE | AURKB, AURKA, AURKC | POLB 1728/4885ALDH1A1 1984/4885RORC 1924/4885 |
| US-10017513-B2 | Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido [5,4-D][2]benzazepin-2-YL]amino}-2-methoxybenzoate | AURKA, AURKB, AURKC | POLB 1260/4885ALDH1A1 2582/4885RORC 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.