Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19088851 | 1.00 | EPHX1 (0.41) | EPHX1CHRM3L3MBTL1GFERDRD2 | |
| SCHEMBL21739082 | 0.92 | GFER (0.41) | EPHX1L3MBTL1GFERDRD2KMT2A | |
| SCHEMBL28276400 | 0.81 | MEN1 (0.41) | EPHX1L3MBTL1GFERDRD2KMT2A | |
| SCHEMBL8038051 | 0.81 | EPHX1 (0.43) | EPHX1CHRM3L3MBTL1DRD2KMT2A | |
| SCHEMBL8055435 | 0.81 | EPHX1 (0.43) | EPHX1CHRM3L3MBTL1DRD2KMT2A | |
| SCHEMBL1922016 | 0.80 | DRD2 (0.43) | EPHX1L3MBTL1GFERDRD2KMT2A | |
| SCHEMBL28539035 | 0.80 | ITGB3 (0.38) | EPHX1GFERDRD2KMT2AMEN1 | |
| SCHEMBL28539036 | 0.80 | ITGB3 (0.38) | EPHX1GFERDRD2KMT2AMEN1 | |
| SCHEMBL28539034 | 0.80 | ITGB3 (0.38) | EPHX1GFERDRD2KMT2AMEN1 | |
| SCHEMBL20608338 | 0.79 | GLP1R (0.46) | CHRM3L3MBTL1KMT2AALDH1A1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117556-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE GLP-1 RECEPTOR | VANDERBILT UNIVERSITY (US) | 2017-07-06 | — | — | WO | disclosed |