SCHEMBL19089345 — predicted protein targets

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	2/20	0.40

▸	RAB9A	P51151	1/20	0.40

▸	DUSP3	P51452	1/20	0.40

▸	PTPN11	Q06124	1/20	0.40

▸	SRC	P12931	2/20	0.39

▸	FGFR1	P11362	2/20	0.38

▸	FGFR3	P22607	8/20	0.37

▸	GAA	P10253	1/20	0.36

▸	ALOX15	P16050	1/20	0.36

▸	TSHR	P16473	1/20	0.36

▸	CYP3A4	P08684	2/20	0.35

▸	CYP2C19	P33261	2/20	0.35

▸	CYP1A2	P05177	1/20	0.35

▸	EGFR	P00533	1/20	0.35

▸	ERBB3	P21860	1/20	0.35

▸	CYP2C9	P11712	1/20	0.35

▸	CHEK1	O14757	1/20	0.35

▸	ERBB2	P04626	1/20	0.35

▸	BRD4	O60885	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20549034	0.86	FGFR1 (0.48)	FGFR1EGFR
SCHEMBL35210276	0.86	FGFR1 (0.48)	FGFR1EGFR
SCHEMBL19089339	0.71	KDR (0.46)	SRCFGFR1FGFR3CYP3A4EGFR
SCHEMBL35210268	0.71	EGFR (0.60)	FGFR1EGFR
SCHEMBL19089330	0.71	EGFR (0.60)	FGFR1EGFR
SCHEMBL19089335	0.70	SRC (0.42)	SRCFGFR1GAAEGFR
SCHEMBL19089568	0.70	INSR (0.43)	DUSP3PTPN11FGFR3CYP3A4EGFR
SCHEMBL19089338	0.69	SRC (0.53)	SRCFGFR1EGFRERBB2
SCHEMBL19089420	0.68	FGFR1 (0.52)	SRCFGFR1EGFRERBB2
SCHEMBL35210289	0.68	FGFR1 (0.52)	SRCFGFR1EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017114500-A1	ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY	恩瑞生物医药科技（上海）有限公司	2017-07-06	—	—	WO	disclosed