Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 15/20 | 0.48 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.44 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089516 | 0.92 | EGFR (0.48) | GALR2EGFRERBB2AURKAINSR | |
| SCHEMBL35210310 | 0.82 | EGFR (0.57) | EGFRERBB2ERBB4GAKRIPK2 | |
| SCHEMBL20548791 | 0.82 | EGFR (0.57) | EGFRERBB2ERBB4GAKRIPK2 | |
| SCHEMBL28056977 | 0.79 | EGFR (0.55) | EGFRERBB2AURKAINSRFBP1 | |
| SCHEMBL2203223 | 0.78 | EGFR (0.55) | EGFRTNNI3KERBB2ERBB4AURKA | |
| SCHEMBL19089509 | 0.78 | EGFR (0.61) | EGFRERBB2ERBB4GAKRIPK2 | |
| SCHEMBL20655477 | 0.76 | EGFR (0.57) | EGFRJAK3KCNH2 | |
| SCHEMBL19089675 | 0.75 | EGFR (0.49) | EGFRERBB2ERBB4SRCAURKA | |
| SCHEMBL7777464 | 0.75 | EGFR (0.61) | EGFRERBB2AURKAINSRFBP1 | |
| SCHEMBL19089514 | 0.75 | EGFR (0.58) | EGFRERBB2JAK3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |