Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.64 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078987 | 1.00 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1KDM4EGAA | |
| SCHEMBL19078980 | 0.84 | CYP4A11 (0.60) | CYP4F2CYP4A11ALDH1A1KDM4EGAA | |
| SCHEMBL28968728 | 0.83 | SIGMAR1 (0.64) | MAPTHDAC1 | |
| SCHEMBL19078992 | 0.83 | CYP4A11 (0.76) | CYP4F2CYP4A11ALDH1A1KDM4EMAPT | |
| SCHEMBL4197208 | 0.82 | CYP4F2 (0.56) | CYP4F2CYP4A11ALDH1A1KDM4EGAA | |
| SCHEMBL5724917 | 0.82 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1GAALOXL2 | |
| SCHEMBL19078976 | 0.82 | CYP4A11 (0.57) | CYP4F2CYP4A11ALDH1A1KDM4EGAA | |
| SCHEMBL19078986 | 0.81 | CYP4A11 (0.78) | CYP4F2CYP4A11ALDH1A1KDM4EMAPT | |
| SCHEMBL19438607 | 0.81 | SIGMAR1 (0.61) | MAPT | |
| SCHEMBL19438673 | 0.81 | HDAC1 (0.50) | ALDH1A1KDM4EHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233148-B2 | Aromatic ionizable cationic lipid | ARCTURUS THERAPEUTICS, INC. (US) | 2019-03-19 | — | — | US | disclosed |
| US-20180050987-A1 | AROMATIC IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS, INC. | 2018-02-22 | — | — | US | disclosed |
| US-9834510-B2 | Aromatic ionizable cationic lipid | ARCTURUS THERAPEUTICS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| WO-2017117530-A1 | IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS, INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| US-20170190661-A1 | Aromatic Ionizable Cationic Lipid | ARCTURUS THERAPEUTICS, INC. | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233148-B2 | Aromatic ionizable cationic lipid | SGMS1, SLCO4C1, SLCO2B1 | CYP4F2 643/4885CYP4A11 433/4885ALDH1A1 3039/4885 |
| US-20180050987-A1 | AROMATIC IONIZABLE CATIONIC LIPID | SGMS1, SLCO4C1, SLCO2B1 | CYP4F2 643/4885CYP4A11 433/4885ALDH1A1 3039/4885 |
| US-20170190661-A1 | Aromatic Ionizable Cationic Lipid | SGMS1, SLC7A1, SLCO2B1 | CYP4F2 494/4885CYP4A11 476/4885ALDH1A1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.