SCHEMBL19089997

SCHEMBL19089997

c1ccc(-c2ccc(N(c3ccc(-c4ccc(C56CC7CC(CC(C7)C5)C6)cc4)cc3)c3cccc(-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
GFER P55789 1/20 0.39
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
HTT P42858 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MAPT P10636 1/20 0.37
EPHX2 P34913 2/20 0.36
HSD11B1 P28845 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24421735 1.00 LMNA (0.41) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL24422264 1.00 LMNA (0.41) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL22815629 1.00 LMNA (0.41) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL24422020 1.00 LMNA (0.41) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL23691251 0.99 LMNA (0.42) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL26368021 0.94 MEN1 (0.38) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL24421868 0.94 MEN1 (0.38) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL22815313 0.93 LMNA (0.36) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL24422008 0.93 LMNA (0.47) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL24422010 0.93 LMNA (0.47) LMNAALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116168-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 머티어리얼사이언스 주식회사 2017-07-06 WO disclosed