SCHEMBL22815313

SCHEMBL22815313

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc(N(c5ccc(C67CC8CC(C6)C(C8)C7)cc5)c5cccc(-c6ccccc6)c5)cc4)cc3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.33
HTT P42858 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
POLB P06746 1/20 0.33
GFER P55789 1/20 0.33
MAPT P10636 1/20 0.33
EPHX2 P34913 3/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24421735 0.93 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1
SCHEMBL24422264 0.93 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1
SCHEMBL19089997 0.93 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1
SCHEMBL24422020 0.93 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1
SCHEMBL22815629 0.93 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1
SCHEMBL22815379 0.93 LMNA (0.40) LMNAALDH1A1GAAHTTMEN1
SCHEMBL23691251 0.92 LMNA (0.42) LMNAALDH1A1GAAHTTMEN1
SCHEMBL22815360 0.92 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1
SCHEMBL25903972 0.92 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1
SCHEMBL26154234 0.92 LMNA (0.41) LMNAALDH1A1GAAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020253445-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 陕西莱特光电材料股份有限公司 2020-12-24 WO disclosed