Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090593 | 0.86 | BRD4 (0.34) | — | |
| SCHEMBL19090465 | 0.69 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL19090232 | 0.68 | NPC1 (0.43) | — | |
| SCHEMBL19090462 | 0.67 | P2RX3 (0.35) | MEN1KMT2A | |
| SCHEMBL13870209 | 0.66 | RECQL (0.54) | MEN1KMT2A | |
| SCHEMBL19090209 | 0.66 | APOBEC3G (0.47) | MEN1KMT2A | |
| SCHEMBL19090553 | 0.65 | SMN1; SMN2 (0.37) | MEN1KMT2A | |
| SCHEMBL19090464 | 0.64 | P2RX3 (0.36) | MEN1KMT2A | |
| SCHEMBL19090547 | 0.64 | SMN1; SMN2 (0.38) | MEN1KMT2A | |
| SCHEMBL19090323 | 0.64 | BRD4 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114843-A1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-07-06 | — | — | WO | disclosed |