Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090216 | 0.86 | MEN1 (0.35) | — | |
| SCHEMBL19090232 | 0.81 | NPC1 (0.43) | BRD4TP53 | |
| SCHEMBL19090462 | 0.81 | P2RX3 (0.35) | PDE5ATP53 | |
| SCHEMBL19090465 | 0.80 | MEN1 (0.39) | PDE5ATP53 | |
| SCHEMBL19090209 | 0.79 | APOBEC3G (0.47) | TP53 | |
| SCHEMBL19090464 | 0.75 | P2RX3 (0.36) | PDE5ATP53 | |
| SCHEMBL19090224 | 0.75 | MAPT (0.47) | — | |
| SCHEMBL19090323 | 0.74 | BRD4 (0.47) | BRD4BRD2BRD3TP53 | |
| SCHEMBL19090233 | 0.72 | BRD4 (0.34) | BRD4BRD2BRD3 | |
| SCHEMBL19090459 | 0.70 | MEN1 (0.49) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114843-A1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-07-06 | — | — | WO | disclosed |