SCHEMBL190915

SCHEMBL190915

COc1ccc(CC=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
TP53 P04637 1/20 0.65
CYP3A4 P08684 1/20 0.65
ALOX15 P16050 1/20 0.65
TSHR P16473 1/20 0.65
ALOX12 P18054 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
IDO1 P14902 4/20 0.54
CYP2A6 P11509 1/20 0.54
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
AGXT P21549 2/20 0.50
LTA4H P09960 1/20 0.50
CMA1 P23946 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457868 0.94 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL19287149 0.94 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL933579 0.88 APP (0.62) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL14237960 0.87 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL6539948 0.87 PKM (0.68) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL2558138 0.85 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL2334747 0.84 ALDH1A1 (0.49) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL11437812 0.83 ALDH1A1 (0.68) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL244069 0.83 ALDH1A1 (0.68) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL28807469 0.81 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3738 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240114-A1 Improved Combination of Protease and Protease Inhibitor with Secondary Enzyme BASF SE (DE) 2024-07-18 US claimed
CN-118302422-A Substituted N-cyanopyrrolidines having activity as USP30 inhibitors 特殊治疗有限公司 2024-07-05 CN claimed
EP-4157834-B1 N-(1-CYANO-PYRROLIDIN-3-YL)-5-(3-(TRIFLUOROMETHYL)PHENYL)OXAZOLE-2-CARBOXAMIDE DERIVATIVES AND THE CORRESPONDING OXADIAZOLE DERIVATIVES AS USP30 INHIBITORS FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION MISSION THERAPEUTICS LTD (GB) 2024-07-03 EP claimed
CN-118271233-A Nilaparil manufacturing method 特沙诺有限公司 2024-07-02 CN claimed
US-20240209029-A1 ADIPONECTIN GLYCOPEPTIDES AND COMPOSITIONS AND METHODS OF USE THEREOF THE UNIVERSITY OF HONG KONG (CN) 2024-06-27 US claimed
EP-4387673-A1 PROCESS FOR THE PREPARATION OF PEGYLATED ADRENOMEDULLIN, ITS INTERMEDIATES AND USE THEREOF Bayer Aktiengesellschaft (DE) 2024-06-26 EP claimed
CN-118251382-A Catalytic hydrogenation of aromatic nitro compounds 豪夫迈·罗氏有限公司 2024-06-25 CN claimed
US-20240199677-A1 GLYCOSYLTRANSFERASE INHIBITORS UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2024-06-20 US claimed
US-11993569-B2 3-amino-4-halocyclopentene carboxylic acids as inactivators of aminotransferases NORTHWESTERN UNIVERSITY (US) 2024-05-28 US claimed
EP-4368621-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND Applied Pharmaceutical Science, Inc. (CN) 2024-05-15 EP claimed
WO-1999051598-A1 SUBSTITUTED 9H-PYRIDINO[2,3-b]INDOLE AND 9H-PYRIMIDINO[4,5-b]INDOLE DERIVATIVES: SELECTIVE NEUROPEPTIDE y RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1999-10-14 WO claimed
EP-0944597-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-09-29 EP claimed
WO-1998023588-A9 METALLOPROTEINASE INHIBITORS 1998-09-17 WO claimed
WO-1998023588-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-06-04 WO claimed
EP-0657544-B1 Process for preparing optically active glycidate esters SEPRACOR INC (US) 1997-12-29 EP claimed
EP-0440723-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS SEPRACOR INC (US) 1995-08-16 EP claimed
EP-0657544-A1 Process for preparing optically active glycidate esters SEPRACOR, INC. (US) 1995-06-14 EP claimed
US-5274300-A Patent withdrawn after O.G. published SEPRACOR, INC. (US) 1993-12-28 US claimed
EP-0021585-B1 TRUNCATED SOMATOSTATIN ANALOGS AND INTERMEDIATES THEREFOR, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE ANALOGS AMERICAN HOME PRODUCTS CORPORATION (US) 1983-01-19 EP claimed
EP-0021585-A1 Truncated somatostatin analogs and intermediates therefor, processes for their preparation, and pharmaceutical compositions containing the analogs AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-07 EP claimed