Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 4/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.40 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.40 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716966 | 0.79 | CYP1A2 (0.61) | CYP17A1CYP1A2ALDH1A1 | |
| SCHEMBL26970884 | 0.79 | CYP1A2 (0.61) | CYP17A1CYP1A2ALDH1A1 | |
| SCHEMBL20598022 | 0.78 | CCR1 (0.38) | ACVR1HTR6PLATJAK3PTK2 | |
| SCHEMBL20025760 | 0.78 | ACVR1 (0.33) | KHKCYP17A1CYP1A2ACVR1BMPR1B | |
| SCHEMBL31745021 | 0.78 | CCR1 (0.38) | ACVR1HTR6PLATJAK3PTK2 | |
| SCHEMBL6373488 | 0.69 | SLC18A3 (0.76) | SLC18A3SIGMAR1GABRA1GABRB2 | |
| SCHEMBL22051953 | 0.69 | SLC18A3 (0.76) | SLC18A3SIGMAR1GABRA1GABRB2 | |
| SCHEMBL23711766 | 0.65 | KHK (0.62) | KHKALDH1A1 | |
| SCHEMBL31279404 | 0.65 | KHK (0.62) | KHKALDH1A1 | |
| SCHEMBL4574 | 0.65 | SLC18A3 (1.00) | SLC18A3SIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114497-A1 | IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY | NOVARTIS AG (CH) | 2017-07-06 | — | — | WO | disclosed |