SCHEMBL20598022

SCHEMBL20598022

CN(C)C1CCN(S(=O)(=O)c2ccc(-n3ncc4c(-c5ccc(C6CCNCC6)cc5)cccc43)cc2)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 1/20 0.38
▸ HSD11B1 P28845 1/20 0.37
▸ CCNA2 P20248 1/20 0.37
▸ CDK2 P24941 1/20 0.37
▸ USP5 P45974 1/20 0.37
▸ ALOX5AP P20292 1/20 0.36
▸ FEN1 P39748 1/20 0.36
▸ TYMS P04818 1/20 0.36
▸ HTR6 P50406 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ HTT P42858 1/20 0.34
▸ TSHR P16473 2/20 0.34
▸ STAT3 P40763 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ TP53 P04637 2/20 0.34
▸ APOBEC3A P31941 1/20 0.34
▸ APOBEC3G Q9HC16 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ TRPV4 Q9HBA0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31745021 1.00 CCR1 (0.38) CCR1HSD11B1CCNA2CDK2USP5
SCHEMBL20598011 0.84 GPR119 (0.45) LMNATP53JAK3PTK2MEN1
SCHEMBL20025760 0.84 ACVR1 (0.33) JAK3PTK2ACVR1
SCHEMBL20598131 0.79 USP5 (0.44) CCR1HSD11B1CCNA2CDK2USP5
SCHEMBL19092433 0.78 KHK (0.46) HTR6JAK3PTK2PLATACVR1
SCHEMBL1135494 0.68 CCR1 (0.79) CCR1
SCHEMBL22325098 0.66 LMNA (0.74) HTR6LMNAHTTTSHRSMN1; SMN2
SCHEMBL19092139 0.62 KMT2A (0.62) USP5LMNAHTTRAB9ASMN1; SMN2
SCHEMBL26026399 0.62 SCN9A (0.33) CDK2HTR6
SCHEMBL16625191 0.62 TNKS (0.57) HSD11B1USP5LMNATRPV4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382621-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY NOVARTIS AG (CH) 2025-12-18 — — US claimed
EP-4219689-A2 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY Novartis AG (CH) 2023-08-02 — — EP claimed
EP-3397756-B1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY NOVARTIS AG (CH) 2023-03-08 — — EP claimed
CN-110582488-A Immune effector cell therapy with enhanced efficacy 诺华股份有限公司 2019-12-17 — — CN claimed
US-20190298715-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY CHINA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH CO., LTD (CL) 2019-10-03 — — US claimed
US-20190000880-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY NOVARTIS AG (CH) 2019-01-03 — — US claimed
US-20250382621-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY NOVARTIS AG (CH) 2025-12-18 — — US disclosed
EP-4219689-A2 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY Novartis AG (CH) 2023-08-02 — — EP disclosed
EP-3397756-B1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY NOVARTIS AG (CH) 2023-03-08 — — EP disclosed
CN-110582488-A Immune effector cell therapy with enhanced efficacy 诺华股份有限公司 2019-12-17 — — CN disclosed
US-20190298715-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY CHINA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH CO., LTD (CL) 2019-10-03 — — US disclosed
US-20190298715-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY CHINA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH CO., LTD (CL) 2019-10-03 — — US disclosed
US-20190000880-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY NOVARTIS AG (CH) 2019-01-03 — — US disclosed
US-20190000880-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY NOVARTIS AG (CH) 2019-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190298715-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY KDM1B, KDM1A, KDM2A CCR1 166/4885HSD11B1 2395/4885CCNA2 2917/4885
US-20250382621-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY KDM1B, KDM1A, KDM2A CCR1 199/4885HSD11B1 2664/4885CCNA2 3082/4885
US-20190000880-A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY KDM1B, KDM1A, KDM2A CCR1 179/4885HSD11B1 2558/4885CCNA2 2944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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