SCHEMBL190925

SCHEMBL190925

O=c1[nH]cc([N+](=O)[O-])c(=O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
MAPT P10636 3/20 0.47
TSHR P16473 2/20 0.47
CYP1A2 P05177 2/20 0.47
GRIA1 P42261 2/20 0.47
GRIA2 P42262 2/20 0.47
GRIA3 P42263 2/20 0.47
GRIA4 P48058 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
GRIK1 P39086 1/20 0.47
BLM P54132 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIK2 Q13002 1/20 0.47
GRIK3 Q13003 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7123914 0.98 LMNA (0.45) LMNAMAPTTSHRCYP1A2GRIA1
Hydrazine SCHEMBL7121815 0.96 LMNA (0.44) LMNAMAPTTSHRCYP1A2GRIA1
Guanidine SCHEMBL7115879 0.89 LMNA (0.41) LMNAMAPTTSHRCYP1A2GRIA1
SCHEMBL7225377 0.86 KDM4E (0.40) LMNAMAPTTSHRCYP1A2GRIA1
Pimagedine SCHEMBL7117351 0.83 LMNA (0.41) LMNAMAPTTSHRCYP1A2GRIA1
SCHEMBL7122109 0.80 LMNA (0.36) LMNAMAPTTSHRCYP1A2GRIA1
T-Butylacetic Acid SCHEMBL10005013 0.80 LMNA (0.41) LMNAMAPTTSHRCYP1A2GRIA1
T-Butylacetic Acid SCHEMBL21570799 0.80 LMNA (0.41) LMNAMAPTTSHRCYP1A2GRIA1
SCHEMBL7122106 0.80 LMNA (0.36) LMNAMAPTTSHRCYP1A2GRIA1
SCHEMBL10505577 0.79 MAPT (0.46) LMNAMAPTTSHRCYP1A2GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438164-B Method for preparing 3, 6-diaminopyrazine-2, 5-dicarboxylic acid and synthetic intermediate thereof HANGZHOU ZHONGMEI HUADONG PHARMACEUTICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-120114996-A Composite nanofiltration membrane with high permeability and pollution resistance as well as preparation method and application thereof 同济大学 2025-06-10 CN claimed
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
US-12240852-B2 Co-crystals, method and apparatus for forming the same REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-03-04 US claimed
US-20240025864-A1 METHOD FOR PREPARING 3,6-DIAMINOPYRAZINE-2,5-DICARBOXYLIC ACID AND SYNTHETIC INTERMEDIATE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) 2024-01-25 US claimed
EP-4242209-A1 METHOD FOR PREPARING 3,6-DIAMINOPYRAZINE-2,5-DICARBOXYLIC ACID AND SYNTHETIC INTERMEDIATE THEREOF Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) 2023-09-13 EP claimed
CN-116438164-A Method for preparing 3, 6-diaminopyrazine-2, 5-dicarboxylic acid and synthetic intermediate thereof 杭州中美华东制药有限公司 2023-07-14 CN claimed
US-20220195497-A1 HYBRIDIZING all-LNA OLIGONUCLEOTIDES ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-06-23 US claimed
WO-2022096015-A1 METHOD FOR PREPARING 3,6-DIAMINOPYRAZINE-2,5-DICARBOXYLIC ACID AND SYNTHETIC INTERMEDIATE THEREOF 杭州中美华东制药有限公司 2022-05-12 WO claimed
US-5580681-A SOLID ELECTROLYTE, ORGANIC ANODE, SOLID CATHODE E.C.R.-ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1996-12-03 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0390540-B1 Process for preparing an organic compound thin film for an optical device SHARP KK (JP) 1994-08-03 EP claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed
US-5084302-A PROCESS FOR PREPARING AN ORGANIC COMPOUND THIN FILM FOR AN OPTICAL DEVICE SHARP KABUSHIKI KAISHA (JP) 1992-01-28 US claimed
EP-0390540-A2 Process for preparing an organic compound thin film for an optical device SHARP KABUSHIKI KAISHA (JP) 1990-10-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025864-A1 METHOD FOR PREPARING 3,6-DIAMINOPYRAZINE-2,5-DICARBOXYLIC ACID AND SYNTHETIC INTERMEDIATE THEREOF DPYD, GART, DHODH LMNA 3148/4885MAPT 997/4885TSHR 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.